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An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

Studying Camizestrant for certain early breast cancer types.

Recruiting
18-130 years
All
Phase 3

This study is testing if the drug camizestrant helps people with early-stage ER+/HER2- breast cancer, which is a type of cancer that grows in response to hormones like estrogen (ER stands for estrogen receptor positive, and HER2- means the cancer does not have too much of a protein called HER2). After surgery and possibly other treatments like chemotherapy, the study checks if camizestrant is better than usual hormone treatments. People in the study will take their assigned treatment for 7 years, and researchers will check their health for up to 10 years. The main thing they are looking at is how long people stay free from invasive cancer, meaning the cancer hasn't come back or spread.

Key Points:

  • The study lasts up to 10 years, with 7 years of treatment.
  • Participants must have had certain treatments already, like surgery.
  • People can join if they are 18 or older and meet the study's health requirements.
Study details
    Breast Cancer
    Early Breast Cancer

NCT05952557

AstraZeneca

31 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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