This study is for patients with gynecological cancers like uterine, ovarian, cervical, or vulvar cancer. It tests if cryocompression (cooling wraps) with or without cilostazol (a medicine that improves blood flow) can help prevent paclitaxel-induced peripheral neuropathy. Peripheral neuropathy means numbness, tingling, or pain in the hands and feet, which can happen due to a chemotherapy drug called paclitaxel. Participants will be divided into three groups:

• Group A: Receives paclitaxel, cryocompression, and cilostazol.
• Group B: Receives paclitaxel and cryocompression.
• Group C: Receives standard care.

Patients aged 18 or older with gynecological cancer planning to undergo chemotherapy may qualify. They shouldn't have conditions like diabetes with high blood sugar, serious liver problems, or heart issues. Pregnant or nursing women, those unable to follow study rules, or those previously treated with paclitaxel are not eligible.

• The study lasts up to 1 year with follow-ups.
• Participants may need to take cilostazol twice daily.
• Potential benefits include reduced neuropathy symptoms.