This study is testing a new medicine called AVP-786 to help with agitation in people with Alzheimer's disease, a type of memory loss. Agitation means feeling restless or upset. The study will last for 12 weeks, and people in the study will take the medicine twice a day. Some people will get a placebo, which is a pill that doesn’t have any medicine in it, to compare results. About 750 people will join this study at 110 places around the world.

To join, you need to have Alzheimer's disease and be experiencing agitation that affects your daily life. You must also have a caregiver, a person who helps take care of you, who can help with the study tasks. You cannot join if you have other types of dementia or other serious health problems.

• The study lasts 12 weeks and medicine is taken twice daily.
• Participants must have Alzheimer's and significant agitation.
• A reliable caregiver must be available to assist with the study.