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Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED

Testing a new eye solution to help with persistent corneal epithelial defects.

Recruiting
18 years and older
All
Phase 2

This study tests a new eye treatment called KPI-012 for people with **persistent corneal epithelial defect** (PCED), a condition where the surface of the eye doesn't heal properly. About 90 people will join this study in the U.S. Participants will be randomly chosen to receive either the new treatment or a placebo (a substance with no therapeutic effect) for 8 weeks. Researchers will compare how well the eye heals in each group. The whole study lasts around 34 weeks, from start to finish.

  • **Participation Length**: The study takes about 34 weeks.
  • **Visits Needed**: Multiple visits to the study center are required.
  • **Treatment and Risks**: Participants will receive either KPI-012 or a placebo, with risks including possible side effects from the treatment.
Study details
    Persistent Corneal Epithelial Defect

NCT05727878

Combangio, Inc

27 April 2025

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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