This study is testing if a drug called KarXT can help treat psychosis (seeing or believing things that aren't real) in people with Alzheimer's Disease (AD). The study is randomized (participants are chosen by chance) and double-blind (neither the participants nor the researchers know who gets the real drug or a fake one called a placebo). It's for people aged 55 to 90 who have mild to severe AD and psychosis.
Participants will be evaluated using a test called the Neuropsychiatric Inventory-Clinician (NPI-C), which checks for hallucinations (seeing things) and delusions (false beliefs).
- To join, you need to live in the same place for at least 6 weeks and have a study partner who can visit or call you often.
- You cannot join if you have other major mental health conditions or serious medical issues.
- The study lasts a few months, and you'll need to attend several visits for tests and check-ups.
If successful, this study could offer a new way to help people with AD who experience difficult symptoms like hallucinations and delusions.