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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

PedAL Trial: Testing for hard-to-treat or recurring childhood leukemia.

Recruiting
22 years and younger
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is for children and young adults under 22 who have leukemia, a type of blood cancer, that has returned after treatment or is tough to treat. Doctors will collect blood and bone marrow samples to learn more about the leukemia and find better ways to treat it. Bone marrow is the soft tissue inside bones that makes blood cells. If you join the study, doctors will collect samples at the start, after treatment cycles, and if the disease comes back. After finishing the study, there will be follow-up visits every 3 months for 2 years, then every 6 months for 3 more years.

  • Study participation involves regular sample collection and follow-ups.
  • Eligibility includes being under 22 and having specific types of leukemia.
  • Written consent is needed from participants or guardians.
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Study details
    Acute Lymphoblastic Leukemia
    Acute Myeloid Leukemia
    Acute Myeloid Leukemia Post Cytotoxic Therapy
    Juvenile Myelomonocytic Leukemia
    Mixed Phenotype Acute Leukemia
    Myelodysplastic Syndrome
    Myelodysplastic Syndrome Post Cytotoxic Therapy
    Myeloid Leukemia Associated With Down Syndrome

NCT04726241

LLS PedAL Initiative, LLC

31 March 2025

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