Study Overview: This study is testing STAR particles, which are tiny particles with microneedles that create small holes in the skin to help topical (applied to the skin) medicines work better. No active medicines will be used in this study. Participants will have STAR particles applied to their arms and hands under different pressures to find the best method.
- **Duration**: 2 visits - first for medical information, second for STAR particle application.
- **Compensation**: Not mentioned.
- **Risks**: Minimal, involves small skin punctures.
Eligibility: Healthy adults aged 18-39 can join if they don't have skin issues, allergies to aloe vera or alumina, or certain medical conditions. Pregnant women or those wanting to get pregnant soon cannot participate. Participants should not have used any skin products on their forearms in the last 24 hours or be part of another study. The study aims to improve how we apply topical treatments by overcoming the skin's natural barrier. Participants will help find the best way to apply STAR particles safely and effectively.