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Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

Genetic testing for early-stage lung cancer patients before or after surgery.

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study, called the ALCHEMIST Screening Trial, looks at genetic testing for patients with certain types of lung cancer, called stage IB-IIIA non-small cell lung cancer (NSCLC). NSCLC is a type of lung cancer that is not small cell. The trial aims to find out if genetic changes in a patient's tumor can help doctors choose the best treatment.

Primary Goals: The trial tests the tumor for genetic changes to help patients join other treatment studies. It also gathers information about the tumor and patient for more research with the National Cancer Institute.

  • The study involves two steps: screening and treatment.
  • Patients need to provide blood and tissue samples for testing.
  • Treatment, if eligible, could last up to 2 years.

Participants must be at least 18 years old, have had or plan to have surgery for their lung cancer, and not have received certain therapies before. No pregnant or breastfeeding individuals can join. This study helps doctors better understand lung cancer and possibly improve treatments.

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Study details
    Stage IB Lung Non-Small Cell Carcinoma AJCC v7
    Stage II Lung Non-Small Cell Cancer AJCC v7
    Stage IIA Lung Cancer AJCC v8
    Stage IIB Lung Cancer AJCC v8
    Stage IIIA Lung Cancer AJCC v8
    Stage IIIA Lung Non-Small Cell Cancer AJCC v7
    Stage IIIB Lung Cancer AJCC v8

NCT02194738

National Cancer Institute (NCI)

16 March 2025

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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