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ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)

Join a study on ARX788 for advanced HER2-positive breast cancer.

Recruiting
18 years and older
All
Phase 2

**ARX788** is a medicine studied for people with **HER2-positive metastatic breast cancer**. This means the cancer has spread to other parts of the body and has high levels of a protein called HER2. The study is **Phase 2**, which tests how well the drug works and its safety. Patients get **ARX788** through an IV (intravenous) every three weeks. You can join if you're 18 or older, have been treated with a drug called **T-DXd**, and your cancer cannot be removed by surgery. You must have no more than five previous treatments for this cancer and at least one tumor that can be measured. You should not have serious heart, lung, or eye problems, or any severe infections. You need to be able to understand and sign a consent form.

  • **Study Duration**: Every 3 weeks, ongoing treatment.
  • **Visits Needed**: Regular visits for IV treatment.
  • **Risks**: Possible side effects include reactions, lung issues, or heart problems.
Study details
    HER2 Positive Metastatic Breast Cancer

NCT04829604

Ambrx, Inc.

31 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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