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Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma

Exploring ketorolac for lung and kidney cancer surgery relief.

Recruiting
18-80 years
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing if a medicine called **ketorolac** can help patients who have surgery for certain types of cancer: non-small cell lung cancer (NSCLC) and renal cell carcinoma (RCC). Ketorolac is a kind of drug known as a non-steroidal anti-inflammatory drug (NSAID), often used to reduce pain and swelling. Researchers think giving it before surgery might help stop cancer from coming back by reducing inflammation that surgery can cause. Inflammation after surgery can sometimes help cancer cells survive and spread. In this study, 56 patients will receive ketorolac before surgery, and 20 will not, to compare results. The study lasts for 28 days after surgery, and medical records will be checked for up to 2 years to see how patients are doing. This research could help find better ways to treat cancer during surgery.

  • Participants will be in the study for 28 days post-surgery.
  • Medical records will be reviewed at 1 and 2 years after surgery.
  • Patients are randomly chosen to receive ketorolac or not.
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Study details
    Non-small Cell Lung Cancer
    Renal Cell Carcinoma

NCT04495894

Emory University

12 October 2024

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