The PEERLESS II Study is looking at ways to treat people with intermediate-risk acute PE, which is a condition where blood clots block blood flow to the lungs. The study compares two treatments: one uses a device called the FlowTriever System along with blood-thinning medicines (anticoagulation), and the other uses blood-thinning medicines alone.

To join, you must be over 18, have specific signs of PE confirmed by medical imaging, and have had symptoms start within the last 14 days. You also need to agree to the study rules. You cannot join if you have certain health issues like unstable blood pressure, allergies to imaging dyes, or if you're already in another study.

Key Points:

• The study may involve using the FlowTriever System, a device for removing clots.
• Participants must visit the study center for check-ups and follow the study plan.
• There are certain health criteria and conditions that might prevent participation.