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A Study of Avutometinib for People With Solid Tumor Cancers

Join a study on Avutometinib for solid tumor cancer patients.

Recruiting
3-30 years
All
Phase 1

This study is testing a medicine called avutometinib for children and young adults with serious solid tumor cancers. Solid tumors are lumps of cancer cells. The study aims to know if this medicine is safe and what dose is best without causing many side effects. You can join if you are between 3 and 30 years old, have a specific type of cancer, and meet certain health conditions. You must also be able to swallow pills and not be pregnant or breastfeeding.

  • Participation Length: The study requires regular visits to the hospital for check-ups and tests.
  • Eligibility: Must have a certain type of cancer and be in the age range of 3 to 30 years old.
  • Risks: There might be side effects, and you need to stop certain medicines before joining.

Before joining, you or your parents will need to sign a consent form. The study will help doctors find out if avutometinib can be a safe treatment for these tough cancers. If you have questions, it’s best to talk to your doctor about whether this study is right for you.

Study details
    Refractory Cancer
    CNS Tumors
    CNS Tumor
    Adult
    CNS Tumor
    Childhood
    MAP Kinase Family Gene Mutation
    NF1
    Plexiform Neurofibroma
    Low-grade Glioma
    Optic Pathway Gliomas
    Neuroblastoma
    Primary Brain Tumor
    Solid Tumor
    Solid Tumor
    Adult
    Solid Carcinoma
    Central Nervous System Tumor

NCT06104488

Memorial Sloan Kettering Cancer Center

27 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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