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AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

Participate in a study for B-cell Acute Lymphoblastic Leukaemia treatment.

Recruiting
12-80 years
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a new medicine called AZD0486 for people with **B-cell Acute Lymphoblastic Leukemia** (B-ALL), a type of blood cancer. It's for patients whose cancer has returned or didn't get better after 2 or more treatments. The study has 3 parts: finding the right dose (Part A), adjusting the dose (Part B), and testing the dose (Part C). Participants should be 16 years or older for Part A, and 12 years or older for Parts B and C. The study checks how safe and effective AZD0486 is.

  • The study requires multiple visits to the clinic.
  • There might be side effects from the medicine.
  • Participants won't receive any other cancer treatments during the study.

People with certain brain issues or other cancers can't join. Also, if you've had specific cancer treatments recently, you may not qualify. Participants will be closely monitored, and the study aims to find the best dose that works safely. Make sure to talk with your doctor to see if joining this study is right for you.

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Study details
    B-cell Acute Lymphoblastic Leukemia (B-ALL)

NCT06137118

AstraZeneca

6 April 2025

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Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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