Study Summary: This study is testing a new treatment for people with a kind of brain cancer called glioblastoma multiforme (GBM). The treatment uses a person's own cancer cells to make a vaccine. This vaccine helps the body make special cells, called neoantigen-specific T cells, that can fight cancer. These T cells are taken from the blood, grown in large numbers, and then put back into the patient to help fight the cancer.
- Length: The study involves surgery, vaccinations, and follow-up with MRIs.
- Visits: Participants will have follow-up visits and MRIs to check progress.
- Risks: Potential side effects and the need for close medical follow-up.
Who can join? People with newly diagnosed GBM who have not been treated before, have good kidney and liver function, and are not on certain medications.
Who cannot join? People with another serious disease, active autoimmune disease, or who are pregnant cannot participate.
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