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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

Study testing abeLacimab's safety for atrial fibrillation patients.

Recruiting
65 years and older
All
Phase 3

The LILAC-TIMI 76 study is looking at the effectiveness and safety of a medicine called abelacimab in people with Atrial Fibrillation (AF). AF is a condition where the heart beats irregularly. This study is for people who can't take regular blood-thinning pills, also known as oral anticoagulation. Abelacimab will be compared to a placebo, which is a harmless pill that looks like the real medicine but has no effect. The study wants to see if abelacimab helps prevent stroke or blood clots in these patients. To join, you must be 65 or older and have AF. You also need a record of being unsuitable for other blood-thinners due to risks like bleeding.

  • Study involves multiple visits to the study center.
  • Participants may receive compensation for their time and travel.
  • Discuss potential risks and benefits with your doctor before joining.

This study is important for those who can't take normal blood thinners due to risks. If interested, talk to your doctor to see if you qualify and to understand more about the study process.

Study details
    Atrial Fibrillation (AF)

NCT05712200

Anthos Therapeutics, Inc.

11 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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