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Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Use Escalation Among Young Adult Electronic Nicotine Delivery Systems Users

Studying brain scans to understand young adults' e-cigarette use.

Recruiting
18-25 years
All
Phase N/A

Study Overview: This study is looking at 180 young adults who use electronic cigarettes, or vapes, but do not smoke regular cigarettes. The main goal is to see how their brains respond to anti-vaping messages and predict future nicotine use. Participants will have a brain scan using a special machine called an fMRI, which helps researchers see brain activity.

  • The study lasts for 1 year, with in-person visits every 3 months.
  • Participants will get weekly messages about the dangers of vaping and fill out short online surveys.
  • No smoking regular cigarettes in the past 30 days is allowed for participation.

What to Expect: Participants will visit the University of Georgia to get their brains scanned and provide breath and urine samples to check nicotine levels. They’ll receive weekly emails or text messages with anti-vaping public service announcements (PSAs) and answer questions about them. There will be in-person check-ups every 3 months to confirm smoking status and nicotine use. Participants will be randomly assigned to see different types of PSAs, which will change after 6 months.

Study details
    Message Exposure (sequence: Regular Then Flavor)
    Message Exposure (sequence: Flavor Then Regular)
    No Message Exposure (control Condition)

NCT05447325

University of Georgia

31 March 2025

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