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Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Exploring radiation timing before or after brain surgery in a trial.

Recruiting
18 years and older
All
Phase 3
This study is about treating brain metastases, which is when cancer spreads to the brain. It compares two treatments: **stereotactic radiosurgery (SRS)**, a special type of radiation, given either before or after surgery. The goal is to see which method works better at stopping tumors from growing or coming back. Patients in the study are divided into two groups. One group gets SRS before surgery; the other gets it after. **Key Points:** - **Length of Study:** After treatment, follow-ups are every 3 months for 2 years, and then every 6 months for 2 more years. - **Eligibility:** To join, you need 1 to 4 brain metastases and must be able to handle surgery and SRS. You're not eligible if you've had certain brain treatments before. - **Compensation:** Not mentioned, but you should discuss this with the study team. Inclusion requires brain metastases confirmed by an MRI. Participants need to be 18 or older and in good enough health for surgery and SRS. The study excludes those with previous brain radiation at the surgery site or certain types of cancer. Always discuss potential benefits and risks with your doctor before joining any study.
Study details
    Metastatic Malignant Neoplasm in the Brain

NCT05438212

NRG Oncology

11 May 2025

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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