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A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

Studying Milvexian effects after recent heart issues.

Recruiting
18 years and older
All
Phase 3

This study checks if a medicine called milvexian helps reduce serious heart problems after a recent heart issue, known as an acute coronary syndrome (ACS). ACS includes problems like a heart attack or severe chest pain. The study compares milvexian to a placebo, which is a pill with no active medicine, while participants also receive regular heart care.

  • Participants need to have had a heart problem in the last 7 days.
  • Participants should have two or more risk factors like being 65+, having diabetes, or a history of heart issues.
  • Women who might have children must test negative for pregnancy and cannot be pregnant or breastfeeding.

People cannot join if: their heart attack was due to something other than ACS, they need certain heart surgeries after joining, or have a high risk of bleeding.

Joining involves taking medicine and regular follow-ups. Please consider if you meet criteria and discuss with your doctor if this study is suitable for you.

Key Points:

  • Study duration and visits will be shared at sign-up.
  • Participants may receive compensation.
  • Consider potential risks related to bleeding.
Study details
    Acute Coronary Syndrome

NCT05754957

Janssen Research & Development, LLC

3 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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