Image

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Studying blood thinners for new heart rhythm changes after heart surgery.

Recruiting
18 years and older
All
Phase 3

This study looks at the best way to prevent blood clots in patients who get a heart rhythm problem called *atrial fibrillation (AF)* after heart surgery called *coronary artery bypass graft (CABG)*. AF is when the heart beats irregularly. Blood clots can cause strokes or heart attacks. The study compares two treatments: one uses *oral anticoagulation (OAC)*, which are medicines like *warfarin* or *apixaban* that help prevent clots, and the other uses only *antiplatelet* medicines, like *aspirin*. The study will check how well these treatments work over 90 days and if they cause bleeding.

  • The study lasts for 90 days with follow-ups at 30, 60, and 180 days.
  • Participants will be randomly assigned to either OAC with antiplatelet or antiplatelet-only therapy.
  • For those not in the main study, there is an option to join a registry study with a brief survey.

Patients over 18 who had CABG surgery and developed new AF may join the study, unless they have certain health issues like other heart surgeries or serious liver disease. Up to 500 patients can also join a digital health study using a heart monitor.

Study details
    Atrial Fibrillation
    Stroke
    Bleeding

NCT04045665

Icahn School of Medicine at Mount Sinai

31 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

  Other languages supported:

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.