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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

Testing Volixibat for itch relief in Primary Biliary Cholangitis patients.

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is testing a new medicine called **volixibat** to help with itching (pruritus) caused by a liver disease called **Primary Biliary Cholangitis (PBC)**. PBC is a condition where the bile ducts in the liver get damaged, leading to liver problems and itching. This study wants to see if volixibat can help reduce the itching and slow down the progression of PBC.

Eligibility: To join, you must be 18 years or older, have a confirmed PBC diagnosis, and agree to attend all study visits. People with itching not caused by PBC or with certain other liver issues can’t join.

  • Length of Study: Participants will be involved for the entire study duration, attending all required visits.
  • Compensation: Participants may receive compensation for their time and travel.
  • Risks: As with any study, there may be risks, and it's important to discuss these with your doctor.

If you think you might be eligible and want to help researchers learn more about treating itching in PBC, talk to your doctor about joining this study.

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Study details
    Primary Biliary Cholangitis
    PBC

NCT05050136

Mirum Pharmaceuticals, Inc.

3 May 2025

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