This clinical study is testing a new medicine called JK07 for people aged 18 to 85 with chronic heart failure (a condition where the heart doesn't pump blood as well as it should). It is a Phase 2, randomized, double-blind, placebo-controlled study, meaning some participants get JK07, some get a placebo (a fake medicine), and neither the participants nor the researchers know who gets what. There are two groups: 1) people whose heart's left side pumps less efficiently (≤ 40%), and 2) those with slightly better heart pumping (> 40% and ≤ 65%). The goal is to find out how safe and effective JK07 is.
- The study involves multiple doses and may require several visits.
- Participants must have stable heart failure and follow existing heart medicine plans.
- People with certain heart issues or recent heart surgeries cannot join.