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Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors

Exploring TSR-042 treatment for advanced solid tumors in a clinical trial.

Recruiting
18 years and older
All
Phase 1

The study is testing a new treatment, **dostarlimab**, for patients with advanced solid tumors. Solid tumors are masses of cancer cells, and "advanced" means they have spread or are hard to treat. Dostarlimab is a special type of medicine called a **monoclonal antibody**, which helps the immune system recognize and fight cancer cells. The study has two parts. In Part 1, different doses of dostarlimab are given to find the safest amount. In Part 2, the medicine's safety and effectiveness are tested on specific cancer types.

  • Participants need to visit multiple times over the study period for treatment and assessments.
  • There might be risks like side effects from the medication.
  • Participants may receive the medicine at no cost and may be compensated for their time.
Study details
    Neoplasms

NCT02715284

Tesaro, Inc.

31 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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