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Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

Trial of BMF-219 for certain blood cancers with specific mutations.

Recruiting
18 years and older
All
Phase 1

This study is testing a new medicine called **BMF-219**, which is taken by mouth. It's for adults with certain types of blood cancers, like acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), diffuse large B-cell lymphoma (DLBCL), multiple myeloma (MM), and chronic lymphocytic lymphoma (CLL/SLL). The study will see how much of the medicine is safe and if it helps people. To join, you need to be 18 or older and have one of these cancers that hasn't improved with other treatments.

  • **Study Length**: The study may take several months, with regular visits for check-ups and tests.
  • **Participation**: You need to stop previous treatments and meet certain health conditions to join.
  • **Risks**: Possible side effects and risks related to the new medicine, prior menin inhibitor treatments are not allowed.

If you join, you'll have to visit the doctor often and might need to use birth control. You can't join if you have certain infections, or have had some other treatments or conditions. This study might help find better ways to treat these cancers.

Study details
    Acute Myeloid Leukemia
    Acute Lymphoblastic Leukemia
    Acute Mixed-Phenotype Leukemia
    Cancer
    Refractory
    Progression
    Diffuse Large B Cell Lymphoma
    Multiple Myeloma
    Lymphoma
    Lymphoma
    Non-Hodgkin
    Myeloma
    Plasma-Cell
    Myelomatosis
    Plasma Cell Myeloma
    Chronic Lymphocytic Leukemia
    Small Lymphocytic Lymphoma

NCT05153330

Biomea Fusion Inc.

13 December 2024

Step 1 Get in touch with the nearest study center
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  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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