The NEXUS Aortic Arch Clinical Study is a research project to look at how safe and effective a special medical device called the NEXUS™ Aortic Arch Stent Graft System is. This device is used to treat problems in a part of the body called the aortic arch. The aortic arch is a big blood vessel that carries blood from your heart to the rest of your body. This study is for people with certain conditions like an aortic aneurysm, which is when the aorta gets too big, or other serious issues with the aortic arch.

To participate, you need to be at least 18 years old and have a suitable aorta size. You should not have had certain recent surgeries or other specific medical conditions. People who are pregnant or have certain allergies cannot join. You will need to be available for follow-up visits as part of the study.

• Study will take place at multiple centers.
• Participants must be willing to comply with study procedures.
• Not suitable for people with acute conditions needing immediate treatment.