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A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants ≥ 18 Years of Age With Asthma

Assessing safety of asthma inhalers with different propellants in adults.

Recruiting
18 years and older
All
Phase 3

This study looks at how safe and tolerable a medicine called **salbutamol** is for people 18 and older who have **asthma**. Asthma is a condition that makes it hard to breathe. Salbutamol helps open up airways, making it easier to breathe. The medicine is given through an inhaler, which is a small device you breathe into. The inhaler uses a **propellant**, a gas that helps deliver the medicine. The study compares two types of propellants: **HFA-152a** and **HFA-134a**.

Participants must have had asthma for at least 6 months and be using certain asthma treatments. They will need to stop using some medications before certain tests. The study will check if participants' breathing improves after using the inhaler.

  • The study lasts for 3 months.
  • Participants must have stable asthma without recent severe attacks.
  • There might be brief stops in some medications for testing purposes.

This study helps understand which inhaler propellant is safer and more comfortable for people with asthma.

Study details
    Asthma

NCT06261957

GlaxoSmithKline

13 April 2025

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