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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

Exploring new CAR T Cell therapy for tough multiple myeloma cases.

Recruiting
18 years and older
All
Phase 2

This study looks at a new treatment called Arlocabtagene Autoleucel (BMS-986393). It’s a type of therapy called CAR T Cell Therapy aimed at fighting a blood cancer called multiple myeloma, which comes back or doesn’t respond to other treatments. Multiple myeloma is cancer that affects a person's plasma cells, a type of white blood cell that helps fight infections. The study checks if this treatment is safe and how well it works.

To join, you must have tried at least three different types of treatments for multiple myeloma and seen your disease get worse. You should be in good health overall (ECOG performance status of 0 or 1). You cannot join if your cancer has affected your brain or if you have an active infection.

  • Participants will undergo screening to confirm eligibility.
  • Study duration and number of visits will be explained during enrollment.
  • Potential risks and benefits will be discussed with participants.
Study details
    Multiple Myeloma

NCT06297226

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

21 June 2025

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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