This study looks at how well the medicine Tigulixostat works for people with **gout**. Gout is a type of arthritis caused by too much **uric acid** (a substance in the blood) that can form crystals in joints, causing pain. The study will last for 12 months, and during this time, people will be given either Tigulixostat, Allopurinol (a common gout medicine), or a placebo (a pill with no medicine). This study is "double-blind," meaning neither the participants nor the researchers know who is getting which treatment, to keep it fair.

• The study lasts for a year and involves multiple visits to the clinic.
• Participants must be aged 18-85 and have gout symptoms.
• Participants will be either on urate-lowering medications or not, with specific uric acid levels.

To join, you must not have conditions like secondary hyperuricemia (too much uric acid from another disease) or be experiencing a current gout attack. Remember, this study aims to help find better treatments for managing gout effectively.