The ENLIGHTED study is testing a treatment called padeliporfin VTP for Upper Tract Urothelial Cancer (UTUC), which affects areas like the kidney or ureter. The study involves two phases: Induction and Maintenance. In the Induction Phase, patients get up to 3 treatments about a month apart to try to get rid of the cancer. If successful, they move to the Maintenance Phase for 12 months, with more treatments if the cancer comes back. Afterward, there's a long-term follow-up for up to 48 months to monitor the patient without more treatments.
- Participation can last up to 5 years, including treatment and monitoring phases.
- Patients will have regular check-ups and may need additional treatments if cancer returns.
- Participants must be 18 or older and meet specific health criteria.
To join, you must not have high-grade cancer, certain medical conditions, or be pregnant. Always discuss with your doctor to see if this study is a good fit for you.