Primary sclerosing cholangitis (PSC) is when the liver's bile ducts, which carry bile (a liver-made liquid that helps digest food), get damaged. For children with PSC, this study aims to gather information to better understand the disease and its effects. Information, like DNA and other samples, will be collected to learn more about PSC’s causes and effects. The study will also explore how PSC affects kids' daily lives and their overall functioning. Children aged 2 to 25 with PSC can participate if they meet certain criteria, like having specific bile duct changes or liver tissue findings.
Key Points:
- The study is observational, meaning no new treatment will be given, just data collection.
- Participants may need to visit clinics for assessments and provide blood or tissue samples.
- No compensation is mentioned, but the study helps understand PSC better, possibly aiding future treatments.
Children with PSC must agree to follow study procedures and provide consent. Those with liver transplants or other specific conditions are not eligible. This study’s findings could help develop new PSC treatments in the future.