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Pembrolizumab and Lenvatinib in Advanced Cervical Cancer

Testing Pembrolizumab and Lenvatinib for advanced cervical cancer.

Recruiting
18 years and older
Female
Phase 2

This study is for women with advanced cervical cancer. It tests two medications: pembrolizumab, which helps the immune system fight cancer, and lenvatinib, which may stop blood vessels from feeding tumors. The goal is to see how well these drugs work together. This is a phase II trial, which means it's still in early testing but shows promise in the lab.

The trial has two stages. In the first stage, 11 women will participate. If 2 or more respond well, 24 more will join for a total of 35. The trial will check how many respond positively. If 9 or more out of 35 show improvement, the treatment will be studied further.

  • Participants must be women aged 18 or older with advanced cervical cancer that didn't respond to other treatments.
  • Participants must not be pregnant or breastfeeding and have certain health conditions.
  • The study requires regular visits and tests to monitor health and treatment effects.
Study details
    Cervical Cancer
    Metastatic Cervical Cancer

NCT04865887

Georgetown University

17 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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