Study Summary: This study tests if a special system, called the XVIVO Heart Perfusion System (XHPS), can safely keep donor hearts healthy for transplant. Donor hearts that don’t meet usual criteria might be preserved and transported using this new method. The process is called Non-Ischemic Heart Preservation (NIHP), which means the heart is kept in good condition without damage from lack of blood flow.

• Participants must be 18 or older and waiting for a heart transplant.
• The study does not allow participants who have had other transplants or need multiple organ transplants.
• No extra visits required beyond normal transplant process.

Important Notes: You need to sign a consent form to join. If you have been part of another clinical trial, you may not be eligible. This study is not randomized, meaning everyone receives the same preservation method. The goal is to see if this method works well to prepare hearts for transplantation and if it is safe for patients.