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CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Exploring new CAR-T cell therapy for certain lymphoma types.

Recruiting
18 years and older
All
Phase 1

Study Overview: This study is for adults with a type of cancer called B cell non-Hodgkin lymphoma that hasn't responded to other treatments. It looks at a new treatment called CB-010, which uses special cells (CAR-T cells) that are changed in a lab to try to fight the cancer.

Participants will first receive medicines called cyclophosphamide and fludarabine to prepare their bodies. Then, they will get the CB-010 treatment. The study will check if this new treatment is safe and how well it works.

Key Points:
  • Duration: The study includes multiple visits to the clinic for treatment and monitoring.
  • Eligibility: Participants must be 18 or older and meet certain health criteria.
  • Risks: There are potential risks, and participants will be closely monitored for safety.

Before joining, consider the time commitment, your health status, and discuss with your doctor if this study might be a good fit for you.

Study details
    Lymphoma
    Non-Hodgkin
    Relapsed Non Hodgkin Lymphoma
    Refractory B-Cell Non-Hodgkin Lymphoma
    Non Hodgkin Lymphoma
    Lymphoma
    B Cell Lymphoma
    B Cell Non-Hodgkin's Lymphoma

NCT04637763

Caribou Biosciences, Inc.

30 March 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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