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Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine

Testing Erenumab's effects on children with occasional migraines.

Recruiting
6-17 years
All
Phase 3

Erenumab is a medicine being tested to see if it can help prevent episodic migraines (headaches that happen occasionally) in kids aged 6-17. This study lasts up to 79 weeks, and involves several phases with different treatments and follow-ups. In the beginning, participants will be randomly assigned to get either erenumab (in different doses based on weight) or a placebo (a fake medicine) for 12 to 24 weeks. After that, everyone has a chance to receive erenumab for another 40 weeks. The study will also check how safe it is. To join, kids must have had migraines for at least a year, with 4-14 migraine days a month. They cannot have other severe headaches or been unresponsive to two or more migraine prevention medications.

  • This study is long, lasting up to 79 weeks.
  • Participants might receive different doses of erenumab or a placebo.
  • Participants need to have frequent migraines but cannot have other serious health issues.
Study details
    Migraine

NCT03836040

Amgen

19 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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