This study wants to find out if a drug called edecesertib can help people with Cutaneous Lupus Erythematosus (CLE), a skin disease. The study will look at how the body reacts to the medicine and any side effects.

To join, you must have active CLE now and, if you have Systemic Lupus Erythematosus (SLE), a total score of 4 or more at the start of the study. You'll need to be okay with having a small piece of skin removed for two tests. People who only have mild forms of lupus affecting one body area, or if they have other active skin issues, cannot join. You should have tried other treatments for CLE and not had success.

• Length of Study: Must be able to attend all study visits.
• Compensation: Possible, but details not provided.
• Risks: Potential side effects from the drug and skin biopsy required.

Note: Speak with your doctor if you’re interested and they can help decide if this study is right for you.