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Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Study on Bromocriptine's effects for heart health after childbirth.

Recruiting
18 years and older
Female
Phase 4

This study is looking at how a drug called **bromocriptine** affects women with a heart condition called **peripartum cardiomyopathy (PPCM)**, which can happen after giving birth. **Bromocriptine** is a medicine that can help the heart recover, but it also stops breastfeeding. The study will have two groups: 200 women who take bromocriptine or a fake pill (placebo) and 50 women who choose to keep breastfeeding without taking bromocriptine. The heart function will be checked with a test called an echocardiogram at the start, six months, and twelve months later.

  • The study lasts up to 3 years with regular heart checks.
  • Women taking bromocriptine will also need another medicine to prevent blood clots.
  • Women who want to breastfeed can't take bromocriptine but can still join a separate group for observation.
Study details
    Peripartum Cardiomyopathy
    Postpartum

NCT05180773

Dennis M. McNamara, MD, MS

26 April 2025

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