This study explores how a treatment called **Vagal Nerve Stimulation (VNS)** affects people withdrawing from opioids, like certain pain medications or heroin. A vagus nerve is a nerve in your neck that helps control your body's activities. **VNS** uses a small device to send electrical signals to this nerve, similar to a pacemaker. This study uses a non-surgical device by ElectroCore, which is applied to the neck. It's already approved for treating headaches in the US and other conditions in Europe, and has been tested for PTSD with no bad effects. In this study, VNS is being investigated for its safety and ability to reduce cravings and withdrawal symptoms in people with **Opioid Use Disorders (OUDs)**, even though it's not yet approved for OUDs in the US.
- **Time Commitment:** Stay in a research hospital for about a week.
- **Procedures:** Includes MRI scans, psychiatric interviews, and physical tests.
- **Post Study:** Follow-up call 1-3 months after the stay.
To join, you must have OUDs and be willing to undergo supervised withdrawal. You can't join if you're pregnant, have certain medical conditions, or are on specific treatments. Compensation details were not provided.