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Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine

Testing Erenumab's effects on chronic migraines in kids.

Recruiting
6-17 years
All
Phase 3

This study is testing a medicine called erenumab to see if it helps kids and teens who get bad headaches called chronic migraines. Chronic migraines are headaches that happen a lot, usually more than 15 days a month. The study will compare erenumab to a placebo, which is a fake treatment, to check if it really works. Children aged 6 to 12 and teens aged 12 to 18 can join if they have had migraines for over a year.

The study lasts for several months and has different phases. Some participants get erenumab injections, and some get the placebo. The study will track how many headache days they have each month. Participants will need to use an eDiary to record their headaches, which helps researchers understand the medicine's effect.

  • The study involves visits over about 24 to 40 weeks, including safety checks.
  • Involves taking monthly injections, either erenumab or placebo.
  • Participants will be closely monitored for safety and side effects.

To join, a parent or guardian must agree, and the child must not have other severe health issues or certain types of headaches. The study needs 286 participants to learn if erenumab can help reduce migraine days for young people.

Study details
    Migraine

NCT03832998

Amgen

16 November 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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