This study is exploring a new treatment for ovarian and endometrial cancer that has come back. It combines two drugs, M1774 and ZEN-3694, to find the best dose and check for side effects. These drugs may help stop tumor growth by blocking certain enzymes. The study has two phases: first to find the safe dose, and second to see how well the treatment works in different patients.

Key Points:

• The study involves taking pills and having regular check-ups, including blood tests and scans.
• Participants must have certain types of cancer and meet specific health criteria.
• Women who are pregnant, breastfeeding, or trying to conceive cannot participate due to potential risks.

In this study, researchers will also look at how the drugs move through the body (pharmacokinetics) and how they affect cancer cells (pharmacodynamics). Patients will be monitored for several years after the study to track their health. Those interested need to be able to swallow pills, and additional eligibility requirements apply. Participants may need to have biopsies, which are small tissue samples taken from the tumor, before and during the study.