This study is testing if a hormone called progesterone can help treat glioblastoma, a type of brain cancer that has returned. Progesterone is made naturally in the body and is important in pregnancy. This trial is in the early stages to find the best dose and check for benefits or side effects. Patients will receive daily shots for up to 24 weeks unless their disease worsens or they can't handle the treatment. To join, patients must be at least 18, have a certain level of health, and not have conditions that make MRI scans unsafe, like metal implants.
- The study lasts up to 24 weeks with daily injections.
- Participants must visit the clinic regularly for check-ups.
- Potential risks include side effects from progesterone.
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