This study tests if a combination of two drugs, Fluticasone Propionate and Albuterol Sulfate, helps prevent worsening asthma attacks. It uses a special inhaler called an eMDPI, which stands for integrated electronic module multidose dry powder inhaler. The study compares this combination to the Albuterol inhaler alone to see which is better at reducing severe asthma attacks and if it affects the use of other strong medicines called systemic corticosteroids. These corticosteroids help reduce inflammation but can have side effects. The study also checks if taking the combination is safe and how well people can handle it.

Participation takes at least 28 weeks, but it may last up to about 35 months. The study includes screening, a trial run, and a treatment period. Eligible participants must have had asthma for at least a year and a history of severe attacks.

• Participation may last from 28 weeks to 35 months.
• Must have asthma for a year and past severe attacks.
• Ensure you are not pregnant or trying to become pregnant.