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A Phase 1, Study of BMF-500 in Adults With Acute Leukemia

Studying BMF-500 for adult acute leukemia treatment.

Recruiting
18 years and older
All
Phase 1

This study tests a new medicine called BMF-500 for adults with acute leukemia, a type of blood cancer. BMF-500 is a pill that targets a gene called FLT3, which is often abnormal in leukemia. The study is in its early phase, meaning it's the first time humans are trying this medicine. The study is looking for adults 18 and older who have acute myeloid leukemia (AML), which is a fast-growing cancer of the blood and bone marrow. Participants should have a certain gene mutation or similar conditions and must be physically fit (ECOG status 0-2). They also need good liver and kidney function.

  • The study lasts for about 4 weeks, requiring continuation of certain antifungal medicines if needed.
  • Participants must avoid certain medicines before and during the study.
  • People with heart problems or very high white blood cell counts cannot join.

If you're eligible and interested, this study could be an opportunity to try a new treatment. However, there are risks, and it's important to discuss them with your doctor.

Study details
    Acute Myeloid Leukemia

NCT05918692

Biomea Fusion Inc.

12 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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