This study looks at how different medications can help prevent strokes in people with narrowed brain arteries. **Strokes** happen when blood flow to the brain is blocked or there's bleeding. **Antithrombotic medications** help prevent blood clots, while **antiplatelet medications** stop blood cells from sticking together. This study compares new medications like **rivaroxaban** and **ticagrelor** with a standard one, **clopidogrel**, to see which works best. **Key Points:** - The study lasts **1 year**, with regular check-ups. - Participants must be willing to swallow pills and available for follow-ups. - It's important to be aware of the risks, like potential side effects from the medications. To join, participants must have had a stroke linked to narrowed arteries and be at least 30 years old. Some people with serious health conditions or specific medical histories may not be able to participate. Women who could become pregnant need a negative test and must use contraception during the study. Participants must not be in another conflicting study.