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Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease

Testing Belumosudil and Rituximab for chronic graft-versus-host disease.

Recruiting
18 years and older
All
Phase 2

This study looks at using two drugs, belumosudil and rituximab, to treat a condition called chronic graft-versus-host disease (cGVHD). cGVHD happens when a person's new immune cells from a transplant attack their body. This study is in Phase 2, which means it's checking how safe and effective these drugs are. People can join if they've never been treated for cGVHD, except for taking less than ten days of certain medicines. They also need to be pretty healthy, with good blood and heart functions.

But, if someone has other active infections or certain health issues, they can't join. The study is open-label, so everyone knows what treatment they're getting. Participants will be closely monitored to see how well the drugs work and any side effects.

  • Participants need to have a good health condition to join.
  • The study checks the safety and effectiveness of the drugs.
  • This is a Phase 2 study, focusing on treatment for cGVHD.
Study details
    Chronic Graft Versus Host Disease

NCT06046248

Northside Hospital, Inc.

19 April 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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