The Parkinson Progression Marker Initiative (PPMI) is a research study aimed at finding ways to track the progress of Parkinson's Disease (PD). Parkinson's Disease is a brain disorder that affects movement. This study looks at changes in clinical features (like symptoms), digital outcomes, and biological and genetic markers over time. Participants can include people with PD, those who may develop it (prodromal), and healthy individuals. The goal is to help find markers that show how the disease progresses, which can help in testing new treatments.

• Time Commitment: Participants may be involved in different parts of the study, which means varying time commitments depending on their role.
• Visits: Participants may need to visit medical centers for tests like imaging scans.
• Eligibility: Different criteria apply depending on whether you are healthy, have PD, or are at risk of developing PD, like age and medication use.