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Perioperative Stress Hyperglycemia in General and Vascular Surgery Patients

Study on blood sugar levels during surgery for general and vascular patients.

Recruiting
45-80 years
All
Phase 4

This study is about stress hyperglycemia (SH), which means high blood sugar during stress, like surgery, in people without known diabetes. About 30% of people without diabetes who have surgery get high blood sugar, increasing the chance of complications. The study will see if a diabetes medicine, dulaglutide, can prevent this. Researchers will monitor sugar levels before, during, and after surgery using a device called continuous glucose monitor (CGM). The study includes two parts: observing sugar levels in patients (Aim 1) and giving dulaglutide or a placebo (fake treatment) to see if it helps control sugar levels (Aim 2). Participants are men and women aged 45-80 having general or vascular surgery, with a BMI (body mass index) of 30 or more. They must not have diabetes or take sugar-control medicines. The study is conducted at a research center, with follow-ups for up to 14 days after surgery.

  • Participants must visit the clinic before surgery for tests.
  • The study lasts up to 14 days after surgery.
  • Patients will receive a small payment for participating.
Study details
    Hyperglycemia Stress

NCT04862234

Emory University

12 October 2024

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