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A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Exploring lung cancer treatment options with pembrolizumab and sacituzumab.

Recruiting
18 years and older
All
Phase 3

This study is for adults with a type of lung cancer called Non-Small Cell Lung Cancer (NSCLC) that can be removed with surgery but did not completely go away after surgery. It tests if adding a new drug, sacituzumab tirumotecan, to an existing one, pembrolizumab, helps more than just using pembrolizumab alone. The goal is to see if the combination helps patients stay cancer-free longer. Pembrolizumab is already used to boost the immune system to fight cancer. Sacituzumab tirumotecan is a new drug being tested in this study.

  • Participation Length: You'll need regular check-ups and have your progress monitored closely.
  • Eligibility: You should have a specific type of lung cancer and meet other health criteria.
  • Compensation and Risks: While there may be benefits, there could also be side effects from the treatment.

Before joining, talk to your doctor to understand the risks and benefits. This study is not for everyone, so make sure you meet the criteria and feel comfortable with the process.

Study details
    Non Small Cell Lung Cancer

NCT06312137

Merck Sharp & Dohme LLC

17 May 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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