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Efficacy in iNPH Shunting (PENS) Trial

Join our iNPH Shunting Trial to explore potential benefits!

Recruiting
60 years and older
All
Phase N/A

This study is for patients with Idiopathic Normal Pressure Hydrocephalus (iNPH), a condition where extra fluid in the brain causes walking and memory problems. It involves a small surgery to place a tube called a shunt, which helps drain the extra fluid. The study compares two groups. One group will have the shunt set to 'active' for 3 months, while the other group will have a 'placebo' setting for the same time. After 3 months, everyone will have their shunt adjusted to the 'active' setting.

Key Points:

  • Length: Initial 3-month period followed by adjustments.
  • Visits: Multiple visits for evaluations and shunt adjustments.
  • Eligibility: Must be 60 or older, have a diagnosis of iNPH, and be able to walk with an assistive device.

Participants should understand the procedures and be able to follow study instructions. If you have conditions like secondary NPH, certain psychiatric or gait issues, this study might not be for you. The study requires visits for evaluations and shunt programming. It's important to discuss with your doctor if this trial is a good fit for you.

Study details
    Idiopathic Normal Pressure Hydrocephalus (INPH)

NCT05081128

Johns Hopkins University

11 January 2025

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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