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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

Testing RGN-259 eye drops for safety and effectiveness in NK patients.

Recruiting
18 years and older
All
Phase 3

This study is testing a new eye drop called **RGN-259** to see if it helps people with a condition called **Neurotrophic Keratopathy** (NK). NK is a disease where the eye loses feeling and gets less tears, making it hard for the eye surface to stay healthy. The study compares RGN-259 drops with placebo drops (which have no medicine). To join, you must be at least 18 years old and have an eye issue that doesn't heal with regular treatment.

Key Points:

  • Participants will need to attend multiple study visits and follow instructions.
  • Participants must not have certain eye conditions or recent eye surgeries.
  • Women who can have children must use birth control and men must agree to use contraception.

If you have any conditions that might affect the study, like certain eye diseases, recent surgeries, or are using specific medications, you might not be able to join. Also, if you have allergies to the study drops or have been in other drug studies recently, you may not qualify. If you think you might be eligible, talk to your doctor to see if this study could be right for you.

Study details
    Neurotrophic Keratopathy

NCT05555589

ReGenTree, LLC

13 December 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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