Comprehensive Esophageal Diagnostics Study aims to learn more about a condition called achalasia. Achalasia is when the lower esophageal sphincter (LES), a muscle at the end of the esophagus, doesn't open properly. This study will use a tool called a Functional Lumen Imaging Probe (FLIP) to see how much of the problem is due to muscle stiffness or nerve issues. FLIP is a new technology that measures how the esophagus works by using impedance planimetry, which checks how well electricity moves through the esophagus.

• The study will last till September 30, 2024, and involves visits to Emory University.
• Participants must be 18 or older and speak English.
• People with certain health issues or pregnant women cannot join.

By understanding how achalasia works, doctors hope to treat it earlier and better. Participants will help researchers learn about the role of muscle stiffness in achalasia. Eligible individuals must be diagnosed with achalasia or have a related esophageal disorder. Participants will undergo a diagnostic procedure with anesthesia and may need surgery for treatment. This study could lead to better treatments for achalasia in the future.