This study involves 30 healthy adults who will receive a single dose of an Ebola vaccine to understand how their immune system responds. The researchers will collect blood and tissue samples before and after vaccination to examine responses in the blood, lymph nodes, and bone marrow over time. Ebola Virus Disease is a serious illness with high death rates, causing symptoms like fever and organ failure. The study focuses on a specific Ebola vaccine approved in 2019, which is designed to protect against the disease. The study will check if the vaccine helps the body create a strong and lasting defense.

Key Points:

• Participants need to visit multiple times for blood and tissue sampling.
• The study lasts up to a year to track long-term immune responses.
• Eligibility includes being healthy, not pregnant, and having no prior Ebola vaccination.